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Fecal transplant for Clostridium difficile infection relapses using “pooled" frozen feces from non-related donors

Journal Volume 79 - 2016
Issue Fasc.2 - Letters
Author(s) Eva MarÌa Gutiérrez-Delgado, Elvira Garza-González, Manuel Alejandro MartÌnez-Vázquez, José Alberto González- González, Héctor J. Maldonado-Garza, Soraya Mendoza-Olazaran, Cristina Liliana Hernández-Balboa, Adrián Camacho-Ortiz
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(1) Servicio de InfectologÌa, (2) Servicio de GastroenterologÌa, (3) EpidemiologÌa Hospitalaria, Hospital Universitario Dr José Eleuterio González, Universidad Autônoma de Nuevo Leôn, Monterrey México.

Clostridium difficile infection (CDI) is associated with high morbidity and mortality (1). About 20-50% of pa- tients develop relapses after antibiotic treatment (2,4). Fecal microbiota transplantation (FMT) is an effective, inexpensive and secure treatment option for these pa- tients(1,3), even in immunosuppressed patients(5). Conventional FMT (from fresh or frozen feces) from a healthy related donor (2), has shown effectiveness in approximately 90% of CDI relapses (1,3,4).

© Acta Gastro-Enterologica Belgica.
PMID 27382953